Modal Scarf Poppies in red by VIDA VIDA xkKfoZJCA9

Modal Scarf - Poppies in red by VIDA VIDA xkKfoZJCA9
Modal Scarf - Poppies in red by VIDA VIDA

The Falabella Medium Reversible Faux Brushedleather Tote Blush Stella McCartney Ip1Oq

Regeneron Announces Presentation at the 24th Annual Credit Suisse Healthcare Conference

Tote Bag No 141 by VIDA VIDA t79Thp

Chrysler earrings Metallic V JEWELLERY 5DxLqBsQa

Womens Metropolis M Tote Bag Furla jblerB30X

Leather Passport Case Natural World Hurricane by VIDA VIDA wXmY7A

Full Leaf Earrings in Silver Brass Aluminium Proenza Schouler ompjTE

Regeneron and Icahn School of Medicine at Mount Sinai Announce New Antibody Research Agreement

Regeneron Announces Agreement with BARDA for the Development of New Antibody Treatment for Ebola

Cashmere Silk Scarf COUTURE by VIDA VIDA iaROe

Regeneron Discovery on Cause of Rare Genetic Bone Disease Detailed in Science Translational Medicine Publication

Ron DePinho, who as president of MD Anderson Cancer Center launched its Moon Shots program , sees grand challenges “as grand opportunities to deliver a population-level impact that requires the discovery and application of new knowledge, and therefore a cross-sector, multidisciplinary effort.”

Lots of Upside, Limited Downside

Whatever form a grand challenge takes, it is an effort to pull an organization out of a purely operational mode and create something truly new. That is the both the promise and the peril of any truly ambitious effort, because critics often object to diverting resources from more-pressing needs. Skeptics worry that scientists will spend a lot of time developing solutions that have no definable time horizon or specific application in mind.

However, DePinho pointsout that, over the long haul, grand challenges tend to make good economic sense. “We actually learned that there tends to be so much spinout from a major collective effort that the end result tends to be an increase of effective resources,” he says, because it propels many other efforts forward.

He points to The Cancer Genome Atlas , which sequenced over 10,000 tumor genomes across 33 types of cancer, as an example. As a first-of-its-kind effort, it created a new “periodic table” for cancer research and shifted the field in new directions. It also helped give rise to a similar effort, the Materials Genome Initiative , which hopes to make a LUGGAGE Garment bags Samsonite ckzbEjODcf

For established organizations, grand challenges can also represent managed risk. IBM’s Meyerson points out that projects like Deep Blue, Blue Gene, and Watson differ significantly from his company’s development of the Foldaway Tote Blue Aurora by VIDA VIDA gggLI4
back in the 1960s, which cost $5 billion (about $40 billion in today’s dollars) and could have meant the end of IBM if it failed.

“Grand challenges are not about the amount of money you throw at the problem,” he says. “To run a successful grand challenge program, failure should not be a material risk to the company, but success will have a monumental impact. That’s what makes grand challenges an asymmetric opportunity.”

Meyerson also points out that today’s technology makes the pursuit of ambitious projects far more accessible to smaller organizations: “In the current environment of cloud computing, software as a service, and open data, the opportunities for organizations of any size to pursue grand challenges with minimal capital expenditures is unprecedented.”

No matter what form innovation takes— short, agile sprints or long-term, grand-challenge investments —innovation is fundamentally about solving problems . And the bigger the problems you choose to tackle, the larger the potential payoff. Pursuing a grand challenge won’t improve your results next quarter, but it might just take your enterprise to a whole new level.

Civil unrest

Papua and West Papua Provinces (high risk)We advise against all tourist and other non-essential travel to Papua and West Papua provinces. The security situation remains unpredictable and there is a risk of kidnapping. Political tensions associated with anti-government groups and local rivalries can lead to violent clashes. Sporadic violence has occurred in Papua province, mainly in Jayapura, parts of the central highlands, around the Grasberg mine and on the road between Timika and Grasberg. Clashes between security service personnel and civilians, and between groups of civilians, have resulted in deaths and injuries. If you are travelling to Papua or West Papua provinces, a travel permit known locally as a “surat jalan” is required. Should you need medical attention, limited facilities are available.

Papua and West Papua Provinces

Seismic Activity Indonesia is located in an active seismic zone and is prone to earthquakes, with the potential threat of tsunamis, and volcanic eruptions. Slips, flooding and landslides can occur with little warning, commonly in mountainous and remote areas, but also in urban areas. There are a number of active volcanoes in Indonesia and many have high alert levels which, at times, can necessitate evacuations. These volcanoes erupt from time to time and in the past have caused destruction and loss of life. Ash clouds have also caused disruptions to flights.

Seismic Activity

Mount Agung, an active volcanoon the island of Bali has shown increased volcanic activity since September 2017. The volcano continues tobe activeand the alert levelof Indonesia's Natural Disaster Management Authority can change with little warning.

New Zealanders are advised to exercise caution, check news reports and follow local advice before travelling to areas within Indonesia that are prone to volcanic activity.Daily updates (in Indonesian) can be found on the Indonesian Directorate of Volcanology and Geological Mitigations website and Smithsonian Institution ’s weekly updates. More information is available from the Humanitarian Early Warning Service.

Crime Petty crime is common in Indonesia, including in Bali.Incidents of bag-snatching and pick-pocketing occur and canturn violent.Ensure your personal belongings, passports and other travel documents are secure when walking in public areas and travelling on public transport. Exercise caution, particularly at night.

Credit card fraud, including skimming, is common in Indonesia. We recommend New Zealanders take extra care when using credit cards and ATMs and carefully check credit card statements for fraudulent charges.

There have been incidences of both tourists and Indonesians becoming seriously ill from food and drink spiking. Do not leave food or drink unattended or accept any food or drink from strangers or recent acquaintances.


Foldaway Tote Dusty Roses by VIDA VIDA CPx2sg
Womens Borsa Tracolla Baguette Armani Jeans 8gKgv7n5zU
hat with cotton terry patch Msgm 3rPTJm9z


165 W 1600 N#110LOGAN, UT 84341


M-F 10-7 SAT 10-7



CONTACT US Modal Scarf Collideoscope by VIDA VIDA k1BhU
SD Backpack Superdry aoEaD
Leather Passport Case winters playground pass by VIDA VIDA eHOmt7s0ay
Statement Bag Strawberry Dream by VIDA VIDA 6pOq4T
Unstructured Mrs Thom Jr 28x195x9 Cm With Red White And Blue Shoulder Strap In Pebble Lucido Leather Black Thom Browne KeMNx
COLLABORATE Leather Passport Case Colorado 5 Passport case by VIDA VIDA IesTZD10m


Mens B359 R9426 Beanie Bugatti Nl6gj
Womens Beanie Marc OPolo xrZk8SnEa


MultiWear Wrap Goddess by VIDA VIDA sJBRC
CONTACT US RETURN POLICY Ties On Sale Brown Silk 2017 one size LIVERANO amp; LIVERANO 2017 one size LIVERANO & LIVERANO Silk Ties On Sale KX86q
Sunglasses On Sale Rose Gold 2017 one size Dsquared2 Sunglasses On Sale a4VN97C

have questions?


or email

  • 4th of July SALE going on now!!


  • 4th of July SALE going on now!!