Mens NeonLightPrint Silk Twill Necktie Prada h3Ml6WE

SKU2412883457510128
Mens Neon-Light-Print Silk Twill Necktie Prada h3Ml6WE
Mens Neon-Light-Print Silk Twill Necktie Prada
Menu

Regeneron Named Among Top Two Global Biopharmaceutical Employers by Science Magazine for Fifth Year in a Row

Regeneron Announces Presentation at the 24th Annual Credit Suisse Healthcare Conference

Black Medium BB Round Chain Bag Balenciaga sBWJt

Leather Accent Tag LOVE PAWS by VIDA VIDA t9xoCcl3iJ

Regeneron and Sanofi Announce Publication of Positive Phase 2b Dupilumab Data in The Lancet

Womens Open Disc Stud Earrings Malcolm Betts QwQHe

Black Cat Patch iPhone 7 Case Miu Miu pUVsc

140X140 Herboristerie Scarf in Blue Silk Mussola Christian Lacroix bsOOnvl

Regeneron Announces Agreement with BARDA for the Development of New Antibody Treatment for Ebola

Cashmere Silk Scarf Beauty Scarf by VIDA VIDA FUgn8PjdYw

Silk Square Scarf Chakra Silk Scarf by VIDA VIDA FhqSFuK

Ron DePinho, who as president of MD Anderson Cancer Center launched its Moon Shots program , sees grand challenges “as grand opportunities to deliver a population-level impact that requires the discovery and application of new knowledge, and therefore a cross-sector, multidisciplinary effort.”

Lots of Upside, Limited Downside

Whatever form a grand challenge takes, it is an effort to pull an organization out of a purely operational mode and create something truly new. That is the both the promise and the peril of any truly ambitious effort, because critics often object to diverting resources from more-pressing needs. Skeptics worry that scientists will spend a lot of time developing solutions that have no definable time horizon or specific application in mind.

However, DePinho pointsout that, over the long haul, grand challenges tend to make good economic sense. “We actually learned that there tends to be so much spinout from a major collective effort that the end result tends to be an increase of effective resources,” he says, because it propels many other efforts forward.

He points to The Cancer Genome Atlas , which sequenced over 10,000 tumor genomes across 33 types of cancer, as an example. As a first-of-its-kind effort, it created a new “periodic table” for cancer research and shifted the field in new directions. It also helped give rise to a similar effort, the metallic zipped wallet Comme Des Garons UjWgrMN
, which hopes to make a Swarovski Crystal Bow Necklace Ted Baker jyHRC2
.

For established organizations, grand challenges can also represent managed risk. IBM’s Meyerson points out that projects like Deep Blue, Blue Gene, and Watson differ significantly from his company’s development of the 360 mainframe back in the 1960s, which cost $5 billion (about $40 billion in today’s dollars) and could have meant the end of IBM if it failed.

“Grand challenges are not about the amount of money you throw at the problem,” he says. “To run a successful grand challenge program, failure should not be a material risk to the company, but success will have a monumental impact. That’s what makes grand challenges an asymmetric opportunity.”

Meyerson also points out that today’s technology makes the pursuit of ambitious projects far more accessible to smaller organizations: “In the current environment of cloud computing, software as a service, and open data, the opportunities for organizations of any size to pursue grand challenges with minimal capital expenditures is unprecedented.”

No matter what form innovation takes— short, agile sprints or long-term, grand-challenge investments —innovation is fundamentally about solving problems . And the bigger the problems you choose to tackle, the larger the potential payoff. Pursuing a grand challenge won’t improve your results next quarter, but it might just take your enterprise to a whole new level.

Civil unrest

Papua and West Papua Provinces (high risk)We advise against all tourist and other non-essential travel to Papua and West Papua provinces. The security situation remains unpredictable and there is a risk of kidnapping. Political tensions associated with anti-government groups and local rivalries can lead to violent clashes. Sporadic violence has occurred in Papua province, mainly in Jayapura, parts of the central highlands, around the Grasberg mine and on the road between Timika and Grasberg. Clashes between security service personnel and civilians, and between groups of civilians, have resulted in deaths and injuries. If you are travelling to Papua or West Papua provinces, a travel permit known locally as a “surat jalan” is required. Should you need medical attention, limited facilities are available.

Papua and West Papua Provinces

Seismic Activity Indonesia is located in an active seismic zone and is prone to earthquakes, with the potential threat of tsunamis, and volcanic eruptions. Slips, flooding and landslides can occur with little warning, commonly in mountainous and remote areas, but also in urban areas. There are a number of active volcanoes in Indonesia and many have high alert levels which, at times, can necessitate evacuations. These volcanoes erupt from time to time and in the past have caused destruction and loss of life. Ash clouds have also caused disruptions to flights.

Seismic Activity

Mount Agung, an active volcanoon the island of Bali has shown increased volcanic activity since September 2017. The volcano continues tobe activeand the alert levelof Indonesia's Natural Disaster Management Authority can change with little warning.

New Zealanders are advised to exercise caution, check news reports and follow local advice before travelling to areas within Indonesia that are prone to volcanic activity.Daily updates (in Indonesian) can be found on the Indonesian Directorate of Volcanology and Geological Mitigations website and Cashmere Silk Scarf Renovation by VIDA VIDA 5mtndSP
’s weekly updates. More information is available from the Cashmere Silk Scarf Sureal Pink a by VIDA VIDA 8pSFjW

Crime Petty crime is common in Indonesia, including in Bali.Incidents of bag-snatching and pick-pocketing occur and canturn violent.Ensure your personal belongings, passports and other travel documents are secure when walking in public areas and travelling on public transport. Exercise caution, particularly at night.

Credit card fraud, including skimming, is common in Indonesia. We recommend New Zealanders take extra care when using credit cards and ATMs and carefully check credit card statements for fraudulent charges.

There have been incidences of both tourists and Indonesians becoming seriously ill from food and drink spiking. Do not leave food or drink unattended or accept any food or drink from strangers or recent acquaintances.

SHOP CATEGORIES

shearling monkey mirror bag charm Brown Miu Miu dQJUFo
Cashmere Silk Scarf Indigo confetti by VIDA VIDA 32ItglPjd
Preowned Faco ostrich clutch bag Herm tBubsA
HOUSE + HOME

VISIT ROOLEE

165 W 1600 N#110LOGAN, UT 84341

STORE HOURS

M-F 10-7 SAT 10-7

LET'S BE FRIENDS

CUSTOMER CARE

star print trucker cap Black Givenchy lWm2hq6v
Modal Scarf By The Hours by VIDA VIDA KgqEF
Marmont Petite Alligator Cardholder Red Gucci 7PfRF7a
DEALS + NEWS Punky Jas cashmereblend snood By Walid pPAYq5n
OUR MODELS Black and Pink Chain Wallet Bag Marc Jacobs kqVQHO9
WHOLESALE

ABOUT US

ABOUT US Tote Bag Peace Offering by VIDA VIDA gnsFFWG

LET'S BE FRIENDS

CLOTHING pearl pullthrough earring Metallic Uzerai Edits CB1kvE
Thomas Sabo Bead Nazars eye blue K022063832 Thomas Sabo YTkLzrLT
HOUSE + HOME
CONTACT US Thomas Sabo bracelet A156141512L195v Thomas Sabo vf1JV18F
SHIPPING DELIVERY DEALS + NEWS FIND YOUR SIZE OUR MODELS COLLABORATE WHOLESALE
ABOUT US THE PHOTO LOFT

have questions?

TALK TO US

or email Womens Grey Diamond Huggie Hoops Eva Fehren r7shQuJQ

  • 4th of July SALE going on now!!

  • CLICK FOR A SECRET

  • 4th of July SALE going on now!!

  • CLICK FOR A SECRET