Leather Statement Clutch Prescott Pk LeatherClutch by VIDA VIDA aXRGs

Leather Statement Clutch - Prescott Pk LeatherClutch by VIDA VIDA aXRGs
Leather Statement Clutch - Prescott Pk LeatherClutch by VIDA VIDA

Self tie bow tie Offwhite amp; light grey mix on twill Notch Zd8gB

Modal Scarf hawaii Arts6 by VIDA VIDA vOhwHs

Regeneron Announces an Additional $350 Million Investment and 200 New Jobs in Limerick by End-2017

Leon Purse H13fz Womens Wallets Gerry Weber hLnoB0dnEo

Regeneron and Sanofi Announce Publication of Positive Phase 2b Dupilumab Data in The Lancet

Regeneron Announces Collaboration with Mitsubishi Tanabe Pharma for Investigational Pain Therapy Fasinumab in Asia

Cognac Brown Indie Suede Baker Boy Cap Lock amp; Co Hatters tOflIGCsX

Regeneron and Icahn School of Medicine at Mount Sinai Announce New Antibody Research Agreement

Regeneron Announces Agreement with BARDA for the Development of New Antibody Treatment for Ebola

Regeneron Hires Maya Bermingham as Executive Director, Public Policy

Cashmere Silk Scarf black eyed susans by VIDA VIDA ZdGFfcc

Ron DePinho, who as president of MD Anderson Cancer Center launched its Moon Shots program , sees grand challenges “as grand opportunities to deliver a population-level impact that requires the discovery and application of new knowledge, and therefore a cross-sector, multidisciplinary effort.”

Lots of Upside, Limited Downside

Whatever form a grand challenge takes, it is an effort to pull an organization out of a purely operational mode and create something truly new. That is the both the promise and the peril of any truly ambitious effort, because critics often object to diverting resources from more-pressing needs. Skeptics worry that scientists will spend a lot of time developing solutions that have no definable time horizon or specific application in mind.

However, DePinho pointsout that, over the long haul, grand challenges tend to make good economic sense. “We actually learned that there tends to be so much spinout from a major collective effort that the end result tends to be an increase of effective resources,” he says, because it propels many other efforts forward.

He points to The Cancer Genome Atlas , which sequenced over 10,000 tumor genomes across 33 types of cancer, as an example. As a first-of-its-kind effort, it created a new “periodic table” for cancer research and shifted the field in new directions. It also helped give rise to a similar effort, the Materials Genome Initiative , which hopes to make a Mohair Beanie Red Weekday 5kwBAw

For established organizations, grand challenges can also represent managed risk. IBM’s Meyerson points out that projects like Deep Blue, Blue Gene, and Watson differ significantly from his company’s development of the 360 mainframe back in the 1960s, which cost $5 billion (about $40 billion in today’s dollars) and could have meant the end of IBM if it failed.

“Grand challenges are not about the amount of money you throw at the problem,” he says. “To run a successful grand challenge program, failure should not be a material risk to the company, but success will have a monumental impact. That’s what makes grand challenges an asymmetric opportunity.”

Meyerson also points out that today’s technology makes the pursuit of ambitious projects far more accessible to smaller organizations: “In the current environment of cloud computing, software as a service, and open data, the opportunities for organizations of any size to pursue grand challenges with minimal capital expenditures is unprecedented.”

No matter what form innovation takes— short, agile sprints or long-term, grand-challenge investments —innovation is fundamentally about solving problems . And the bigger the problems you choose to tackle, the larger the potential payoff. Pursuing a grand challenge won’t improve your results next quarter, but it might just take your enterprise to a whole new level.

Civil unrest

Papua and West Papua Provinces (high risk)We advise against all tourist and other non-essential travel to Papua and West Papua provinces. The security situation remains unpredictable and there is a risk of kidnapping. Political tensions associated with anti-government groups and local rivalries can lead to violent clashes. Sporadic violence has occurred in Papua province, mainly in Jayapura, parts of the central highlands, around the Grasberg mine and on the road between Timika and Grasberg. Clashes between security service personnel and civilians, and between groups of civilians, have resulted in deaths and injuries. If you are travelling to Papua or West Papua provinces, a travel permit known locally as a “surat jalan” is required. Should you need medical attention, limited facilities are available.

Papua and West Papua Provinces

Seismic Activity Indonesia is located in an active seismic zone and is prone to earthquakes, with the potential threat of tsunamis, and volcanic eruptions. Slips, flooding and landslides can occur with little warning, commonly in mountainous and remote areas, but also in urban areas. There are a number of active volcanoes in Indonesia and many have high alert levels which, at times, can necessitate evacuations. These volcanoes erupt from time to time and in the past have caused destruction and loss of life. Ash clouds have also caused disruptions to flights.

Seismic Activity

Mount Agung, an active volcanoon the island of Bali has shown increased volcanic activity since September 2017. The volcano continues tobe activeand the alert levelof Indonesia's Natural Disaster Management Authority can change with little warning.

New Zealanders are advised to exercise caution, check news reports and follow local advice before travelling to areas within Indonesia that are prone to volcanic activity.Daily updates (in Indonesian) can be found on the Indonesian Directorate of Volcanology and Geological Mitigations website and Small Leather Goods Wallets Rebecca Minkoff r021AwO
’s weekly updates. More information is available from the Modal Scarf MANYCOLOURS by VIDA VIDA pnjNM7

Crime Petty crime is common in Indonesia, including in Bali.Incidents of bag-snatching and pick-pocketing occur and canturn violent.Ensure your personal belongings, passports and other travel documents are secure when walking in public areas and travelling on public transport. Exercise caution, particularly at night.

Credit card fraud, including skimming, is common in Indonesia. We recommend New Zealanders take extra care when using credit cards and ATMs and carefully check credit card statements for fraudulent charges.

There have been incidences of both tourists and Indonesians becoming seriously ill from food and drink spiking. Do not leave food or drink unattended or accept any food or drink from strangers or recent acquaintances.


CLOTHING Cashmere Silk Scarf pink red cherries by VIDA VIDA 9kmmgb
Tote Bag Sunrise by VIDA VIDA ppnjx2UFSF


165 W 1600 N#110LOGAN, UT 84341


M-F 10-7 SAT 10-7



CONTACT US Womens Mayela/S Vf Sunglasses Gryglttr Gry 50 Jimmy Choo London OAwEgtMs
Women Nylon Cornflower S Nella Shoulderbag Shz Shoulder Bag Joop 0PYKQ3xSW
Drakes 85cm Striped Silk And Cottonblend Faille Tie Kingsman gzySzO3
Black Grenadine Bow Tie Ready Tied Eton XhB4mA
Mens Hilfiger Beanie Tommy Hilfiger 9zpShliTg
Ties On Sale Shaded Grey Silk 2017 one size Balmain 2017 Shaded Grey one size Balmain h8qS5aHDyc




CLOTHING Cashmere Silk Scarf Planetary Cashmere Silk 1 by VIDA VIDA GafsE
Mens Paisley Silk Necktie Paolo Albizzati p2z6FJC00
CONTACT US Beige Ties On Sale Ties On Sale Beige Silk 2017 one size Christian Lacroix one size Christian Lacroix 2017 pw1qkOnQoh
England Cap In White 881712101 White NIKE SPORTWEAR Z4tSGX98
Ri2k Womens Anchika Scoop Bag Ri2K E5dVFEI2rl
ABOUT US Womens Eartha Iconic Satin amp; Leather Mini Crossbody Bag Zac Posen 6auJPQY6

have questions?


or email [email protected]

  • 4th of July SALE going on now!!


  • 4th of July SALE going on now!!