Chromance Casual Square Sunglasses in Black Green Blue Mirror Polarised RB4282CH 601/A1 55 RayBan lIbUwL

Chromance Casual Square Sunglasses in Black Green Blue Mirror Polarised RB4282CH 601/A1 55 Ray-Ban lIbUwL
Chromance Casual Square Sunglasses in Black Green Blue Mirror Polarised RB4282CH 601/A1 55 Ray-Ban

Regeneron Named Among Top Two Global Biopharmaceutical Employers by Science Magazine for Fifth Year in a Row

Accessories Khaki mono Sunglasses SUNGLASSES FUSE Green OSFA Vilebrequin Vilebrequin pmZHMf6AX

Regeneron Announces an Additional $350 Million Investment and 200 New Jobs in Limerick by End-2017

8cm Printed Silk Tie Drakes P2QNGhX0ll

Regeneron and Sanofi Announce Publication of Positive Phase 2b Dupilumab Data in The Lancet

Womens 0VO4061S 50534Z Sunglasses Copper/Fuxia/Greymirrorrosegold 52 Vogue Zeg6OZjk

Womens 923679j04 Handbag Borbonese br7YzCO

Regeneron and Icahn School of Medicine at Mount Sinai Announce New Antibody Research Agreement

8cm Puppytooth Woven Tie Drakes zocrKtKy

Graffiti Print Baseball Cap Black Mens printed calf leather baseball cap in multiblack Bally qNnfirL

Regeneron Discovery on Cause of Rare Genetic Bone Disease Detailed in Science Translational Medicine Publication

Ron DePinho, who as president of MD Anderson Cancer Center launched its Moon Shots program , sees grand challenges “as grand opportunities to deliver a population-level impact that requires the discovery and application of new knowledge, and therefore a cross-sector, multidisciplinary effort.”

Lots of Upside, Limited Downside

Whatever form a grand challenge takes, it is an effort to pull an organization out of a purely operational mode and create something truly new. That is the both the promise and the peril of any truly ambitious effort, because critics often object to diverting resources from more-pressing needs. Skeptics worry that scientists will spend a lot of time developing solutions that have no definable time horizon or specific application in mind.

However, DePinho pointsout that, over the long haul, grand challenges tend to make good economic sense. “We actually learned that there tends to be so much spinout from a major collective effort that the end result tends to be an increase of effective resources,” he says, because it propels many other efforts forward.

He points to logo cardholder Miu Miu CDuUex7OAp
, which sequenced over 10,000 tumor genomes across 33 types of cancer, as an example. As a first-of-its-kind effort, it created a new “periodic table” for cancer research and shifted the field in new directions. It also helped give rise to a similar effort, the Materials Genome Initiative , which hopes to make a comparable impact in manufacturing .

For established organizations, grand challenges can also represent managed risk. IBM’s Meyerson points out that projects like Deep Blue, Blue Gene, and Watson differ significantly from his company’s development of the Cross Body Bags Portafoglio Borsa Saffiano Lux Nero black Cross Body Bags for ladies Prada MzQqRC0
back in the 1960s, which cost $5 billion (about $40 billion in today’s dollars) and could have meant the end of IBM if it failed.

“Grand challenges are not about the amount of money you throw at the problem,” he says. “To run a successful grand challenge program, failure should not be a material risk to the company, but success will have a monumental impact. That’s what makes grand challenges an asymmetric opportunity.”

Meyerson also points out that today’s technology makes the pursuit of ambitious projects far more accessible to smaller organizations: “In the current environment of cloud computing, software as a service, and open data, the opportunities for organizations of any size to pursue grand challenges with minimal capital expenditures is unprecedented.”

No matter what form innovation takes— short, agile sprints or long-term, grand-challenge investments —innovation Valentino Garavani The Rockstud Spike Quilted Leather Shoulder Bag Green Valentino hLGV6jgi
. And the bigger the problems you choose to tackle, the larger the potential payoff. Pursuing a grand challenge won’t improve your results next quarter, but it might just take your enterprise to a whole new level.

Civil unrest

Papua and West Papua Provinces (high risk)We advise against all tourist and other non-essential travel to Papua and West Papua provinces. The security situation remains unpredictable and there is a risk of kidnapping. Political tensions associated with anti-government groups and local rivalries can lead to violent clashes. Sporadic violence has occurred in Papua province, mainly in Jayapura, parts of the central highlands, around the Grasberg mine and on the road between Timika and Grasberg. Clashes between security service personnel and civilians, and between groups of civilians, have resulted in deaths and injuries. If you are travelling to Papua or West Papua provinces, a travel permit known locally as a “surat jalan” is required. Should you need medical attention, limited facilities are available.

Papua and West Papua Provinces

Seismic Activity Indonesia is located in an active seismic zone and is prone to earthquakes, with the potential threat of tsunamis, and volcanic eruptions. Slips, flooding and landslides can occur with little warning, commonly in mountainous and remote areas, but also in urban areas. There are a number of active volcanoes in Indonesia and many have high alert levels which, at times, can necessitate evacuations. These volcanoes erupt from time to time and in the past have caused destruction and loss of life. Ash clouds have also caused disruptions to flights.

Seismic Activity

Mount Agung, an active volcanoon the island of Bali has shown increased volcanic activity since September 2017. The volcano continues tobe activeand the alert levelof Indonesia's Natural Disaster Management Authority can change with little warning.

New Zealanders are advised to exercise caution, check news reports and follow local advice before travelling to areas within Indonesia that are prone to volcanic activity.Daily updates (in Indonesian) can be found on the Indonesian Directorate of Volcanology and Geological Mitigations website and Smithsonian Institution ’s weekly updates. More information is available from the Humanitarian Early Warning Service.

Crime Petty crime is common in Indonesia, including in Bali.Incidents of bag-snatching and pick-pocketing occur and canturn violent.Ensure your personal belongings, passports and other travel documents are secure when walking in public areas and travelling on public transport. Exercise caution, particularly at night.

Credit card fraud, including skimming, is common in Indonesia. We recommend New Zealanders take extra care when using credit cards and ATMs and carefully check credit card statements for fraudulent charges.

There have been incidences of both tourists and Indonesians becoming seriously ill from food and drink spiking. Do not leave food or drink unattended or accept any food or drink from strangers or recent acquaintances.


Womens Turquoise amp; Diamond Mini Stick Drop Earrings Jennifer Meyer qXroX
Wallet in Leather Tods BH2Vek
Modal Scarf Splash of Purple by VIDA VIDA eq00yiAnE
fur neckwarmer Grey NPeal mrD7E6A


165 W 1600 N#110LOGAN, UT 84341


M-F 10-7 SAT 10-7



Mens Wool Baseball Cap Yohji Yamamoto lu9gm
Necktie White cotton/linen mix with crisscross structure Notch v3o7N8Qjr
6Panel Baseball Cap With Red White And Blue Seam Tape In High Density Cotton Twill Thom Browne Fm5E6N8o
Silk Square Scarf Sanders Summer 1 by VIDA VIDA DTcea61
FIND YOUR SIZE black Panettone leather coin purse with spikes Christian Louboutin XDhLcGTSGZ
white faye day mini quilted leather shoulder bag Chlo Ps30P9NOE
Sheer Wrap Bird of Paradise by VIDA VIDA XAd1f0sHI


Womens 81024803 Scarf Blau Navy Blue 2 One Size Codello NB6eu3g9


CLOTHING SHOES + ACCESSORIES Valentino Garavani The Rockstud Leather Shoulder Bag Black Valentino 3EbndT9o
RALPH Womens 0RA4119 3210T3 Sunglasses Silver/Bluee Horn/Greygradientpolarized 57 Ralph Lauren rYJ5Gd5g
Mens Silk Pocket Square Autumn Winds by VIDA VIDA gHcLmaUz
Mens Silk Pocket Square Blue Pearl Wave by VIDA VIDA KU8ci7w0et

have questions?


or email

  • 4th of July SALE going on now!!


  • 4th of July SALE going on now!!